When you attempt to do certain activities in BizTalk360 like resuming service instances, terminating services instances, starting host instances etc. You may see an error message "Unable to enlist in the transaction" as shown below:

Unable to enlist in the transaction.
System.Runtime.InteropServices.COMException (0x8004D00A): Unable to enlist in the transaction.
   at System.Runtime.InteropServices.Marshal.ThrowExceptionForHRInternal(Int32 errorCode, IntPtr errorInfo)
   at System.Management.ManagementObject.InvokeMethod(String methodName, ManagementBaseObject
inParameters, InvokeMethodOptions options)
   at System.Management.ManagementObject.InvokeMethod(String methodName, Object[] args)
at A.cf0555bb9c0f6a0aebd67da53b41e6535.cc49ef4e8476b31546c8cfd44bd22a66(String 


BizTalk server utilizes MS Distributed Transaction Coordinator (MS-DTC) for remote transactions. MS DTC plays an important role in a multi server BizTalk environments. MS DTC in each server must be configured in a certain way as detailed in this article


BizTalk360 uses the underlying BizTalk server API and will require same level of setup on the server where BizTalk360 is installed.